Defending Champions Champions will kick off the 2020/2021 season by hosting Leeds Utd.
It would be the first time in 16 years the Marcelo Bielsa-tutored Leeds will play in the EPL after a dramatic promotion season.
The match holds on September 12 at Anfield.
Tottenham host Everton while Arsenal travel to newly-promoted Fulham.
Chelsea are away to Brighton on the opening weekend.
City and Liverpool are scheduled to meet on the weekends of November 7 at the Etihad and February 6 at Anfield.
Jurgen Klopp’s men do not face traditional rivals Manchester United until 2021 with the Red Devils visiting Anfield on January 16 and Liverpool heading to Old Trafford on May 1.